A substance, e.g., tamoxifenA drug that blocks estrogen from affecting organs, such as the breast. that bind with estrogenA female sex hormone that is primarily produced by the ovaries. Its primary function is to regulate the menstrual cycle and assist in the production of secondary sex characteristics such as breasts. It may even play a role in the production of cancer cells in the breast tissue. receptors to prevent tumorA mass of cells that can be benign or malignant. growth in cases of hormone-sensitive cancer.